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Recombinant Human IFN-β
货 号:AF-300-02B
产品规格:20ug
原 产 地:USA
参考价格:1140 (参考价格,以实际价格为准)
优惠价格:
产品详细信息
Recombinant Human IFN-β
产品编号:
AF-300-02B
别名:
Leukocyte interferon, B cell interferon, Type I interferon
描述:
Proteins of this family play an important role in inducing non-specific
resistance against a broad range of viral infections. They also affect
cell proliferation and modulate immune responses. Produced by
peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid
stable molecule that signals through IFNα/βR, which is also used by
IFNβ. Both IFNs have similar anti-viral activity and regulate
expression of MHC class I antigens. IFNα contains four highly conserved
cysteine residues which form two disulfide bonds, one of which is
necessary for biological activity. Recombinant human IFNβ is an 20.0
kDa protein containing 166 amino acid residues. Manufactured using all non-animal reagents.
氨基酸序列:
MSYNLLGFLQ
RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF
RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL
HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to stimulate the
proliferation of human TF-1 cells. The expected ED50 is ≤ 0.25 ng/ml,
corresponding to a specific activity of ≥ 4 x 106 units/mg.