Capsaicin ab141000 100 mg   abcam

• Product name(E)-Capsaicin
• Description
  Vanilloid receptor (VR1) agonist
• Biological descriptionVanilloid receptor (VR1) agonist (pEC₅₀ values are 7.5 and 6.1 at human and rat VR1 receptors respectively). Antinociceptive and anti-inflammatory effects mediated by primary afferent sensory neurones. Induces reversible inhibition of platelet aggregation.
• Purity> 98%

Properties

• Chemical name(6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
• Molecular Weight305.42
• Chemical structure
• Molecular formulaC₁₈H₂₇NO₃
• CAS Number404-86-4
• PubChem identifier2548
• Storage instructionsStore at +4°C.
• Solubility overviewSoluble in DMSO to 50 mM and in ethanol to 50 mM
• Handling

  Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

• SMILESOc1ccc(cc1OC)CNC(=O)CCCC/C=C/C(C)C
• Source

  Capsicum sp.

Capsaicin≥95%, from Capsicum sp. (Sigma)

M2028-50MG    777元/50mg

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• Holzer P Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 43:143-201 (1991). Read more (PubMed: 1852779) »
• Bevan S & Szolcsányi J Sensory neuron-specific actions of capsaicin: mechanisms and applications. Trends Pharmacol Sci 11:330-3 (1990). Read more (PubMed: 2203194) »