Anti-Mouse/Rat CD29 (Integrin beta 1) FITC

11-0291-80
25ug

USA

The eBioHMb1-1 monoclonal antibody reacts with mouse and rat CD29(integrin beta 1),

a 110-120 kDa member of the beta integrin family expressed byleukocytes, endothelial,
smooth muscle and epithelial cells. CD29 binds non-covalently with thealpha integrins
CD49a-f to form the VLA-1 through VLA-6 complexes, as well as withCD51. These alpha-beta
integrin heterodimers are capable of mediating a variety of cellularresponses including
adhesion, trafficking, proliferaton and differentiation. All integrinswhich include CD29
bind to extracellular matrix proteins including collagen, laminin,fibronectin and vitronectin,
whereas some CD29-containing integrins can also interact with cellularreceptors such as
VCAM-1 and MadCAM-1.